Metatrition Opti Joint Nutritional Supplements, 30 Count

As a person of a certain age, something that offers to improve joint health with increased mobility and flexibility is of interest. Collagen is an important element in the fibrous tissues of the body. The protein provides scaffolding to support skin, makes joints operate smoothly, and is important in tendons and ligaments. So, is taking collagen in capsules an effective way to enhance the body's own collagen?There's the question of how much collagen makes it intact through the digestive process, which is designed to break down proteins among other things, and how much of it is absorbed into the body - and whether it boosts collagen levels once it arrives. I suspect it would take detailed molecular studies to determine this directly; the evidence for the benefits of collagen supplements joint health seems to be based on observed gross health effects - how people feel.The ingredients listed on the bottle include Natural Eggshell Membrane (NEM), UC-II (Natural collagen concentrate) and gelatin, rice flour, and vegetable lubricant. NOTE: IF you have an allergy to eggs, you should use caution before trying this. There is no warning label on the bottle other than "Contains: egg".Collagen can be obtained from a number of natural sources, such as ground-up fish, cow, pig and chicken parts, etc. As such, there is concern that collagen derived from animal tissues may also include less desirable ingredients: heavy metals, antibiotics, viruses, etc. Processing and testing is important. NEM as a collagen source probably avoids many of those issues, but it never hurts to be sure.There is a disclaimer in fine print on the label. It refers to this statement: "Supports healthy joints, joint mobility, joint flexibility." The disclaimer is: "This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease." By marketing this as a food supplement instead of a drug, it is not covered by FDA jurisdiction under the rigorous testing that would be mandated to back up those claims.Ideally, there would be two kinds of testing done. A double-blind study would take a test group of people whose medical condition was documented before the study, and give them two different capsules. One would be the supplement, the other would be an inert capsule. Neither the people taking the capsules or the people handing them out would know which is which. After a test period was done, all of them would be checked to see how their health changed (for better or worse) - and only then would the groups be matched up to which capsules they took.A longitudinal study would follow a group taking the supplement for an extended period of time while monitoring their health. They would be compared with a comparable group not taking the supplement. This would give an idea of long-term health benefits - and risks.If studies of either type have been done for this product, I am not aware of them - which may mean nothing, since I am not doing an extensive search. There are studies claiming benefits from collagen supplements that suggest something may be happening that is useful, but more work needs to be done.The label reports this product was manufactured in a third party inspected GMP facility. (Good Manufacturing Practices) That's all to the good, since GMP is intended to insure that products are consistent and manufactured under safe conditions. The company, Metatrition, is a division of Treadcorp, Ltd. which focuses on "naturally occurring products and services."I haven't yet commented on how well this product works for me. That's because I only just got it and wanted to find out more about it, which I'm sharing here. It's also because it would take time for any benefits to appear - and what works for me might not work for someone else. Self-reporting is always suspect. There's a 30 capsule supply in the bottle, so if I decide to start taking these, it'd be a month before I can report any effects.UPDATE: I've been taking these for nearly a month now, and if they have had any effect, I have not been able to see any difference great enough to notice for good or ill. YMMV.

I study supplementation and believe that by taking the right vitamins and supplements positive health changes occur. I like the ingredients in the formula and think they could have a positive impact on joint health. I have learned that eggshell membrane has glucosamine and is being studied for joint health. I supplement with collagen already but not with the same type found in this formula. I believe collagen has a positive impact on my body based on studies I have read. I like that the ingredients that are found in the formula have been clinically studied. However, I did not feel an impact with this particular formula and wonder if this actual formula has been clinically studied. I do not feel that thirty pills in the bottle are enough to see whether or not the formula will work. I took it as directed and I did not feel a positive change during the month I have taken it. Perhaps it is not strong enough or I am not in such pain that I would notice the impact. I prefer taking my usual supplement routine that has more ingredients for both bone and joint health then this formula. I think it is headed in the right direction and with an increased pill amount and perhaps stronger ingredients I would consider re-ordering.

This supplement may be helpful to some and I liked the idea of protein being supplied via eggs since I'm allergic to meat, however the product disagrees with me. After taking it for about a week, I got to feeling poorly, not really sick, but bloated, uncomfortable and with pain in my liver area. Since I rarely get sick and my innards function well, I didn't know what to make of it, but decided to eat only the mildest of things and lay low for a couple of days. That meant stopping supplements too. I'd put aside regular ones anyway in order to give this product an honest try. After a few days I felt fine again and assumed it was due to something I ate or a bug of some sort. I started back taking the product in order to finish the bottle before reviewing. I didn't expect my aching joints to feel better immediately so wasn't surprised that I noticed no difference there, but after three days taking the supplement again, I'm again feeling poorly with liver pain and bloating. Now I fear it's the supplement itself that just doesn't agree with me. It may have value for others, but I won't be finishing the bottle.

I have on my desk for review the Metatrition Opti Joint Nutritional Supplements, 30 Count. Two ingredients are listed in this supplement. NEM – Natural Eggshell Membrane and UC II Natural Collagen Concentrate. This is what I found on the Internet about these two ingredients. First, Natural Eggshell Membrane (NEM®) is a possible new effective and safe therapeutic option for the treatment of pain and inflexibility associated with joint and connective tissue (JCT) disorders. Supplementation with NEM®, 500 mg taken once daily, significantly reduced pain, both rapidly (seven days) and continuously (30 days). Second, Four clinical studies show that 40 mg of UC-ll® benefits joint comfort, mobility, and flexibility. The undenatured collagen in UC-II® differs from hydrolyzed collagen because it helps protect our naturally occurring type II collagen that slows inflammatory responses.Sounds good. Let me state up front that research is currently in progress concerning these supplements. Readers of this review may or may not be helped by them depending on their unique biochemistry. I have been adding collagen to my morning coffee milkshake and I don’t notice much help with my joints. This new formulation may be more effective. Only time will tell.Final comment: I have tested more than a dozen joint health supplements and some do work better than others. For readers of this review who have sore knees, as I do, it makes sense to keep testing new formulations to see what works best for you.

Because these ended up giving me some pretty fierce gut discomfort, I can’t take them for long enough to ascertain whether they have beneficial effects on my joints.