Difference Between Buccal Absorption and Conventional Oral Administration (Capsules/ Tablets) BUCCAL ABSORPTION Quick, as absorption begins in the oral cavity. Bypasses the hostile environment of the gastrointestinal tract. Rapid absorption and direct entry into the systemic circulation makes the treatment effective and almost instantaneous. Can be taken anywhere and used without water. Safe for both adults and children. Ideal for those suffering from digestive complaints that can hinder the absorption of nutrients. CONVENTIONAL ORAL ABSORPTION Longer transit time through the gastrointestinal tract, influenced by gastric emptying time, presence of food etc.). Hostile gastrointestinal environment leads to degradation of the product. First pass effect and bio-transformation processes determine the drug bioavailability. Needs water to swallow which could be problematic for elderly patients and is unsuitable for young children.
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