--- product_id: 48639981 title: "maxxiSAMe SAM-e Powder for Dogs - Liver & Cognitive Support 150g | Promotes hepatic function, mental sharpness, mood, energy and healthy ageing with artichoke, B vitamins and nutrients" brand: "maxxipaws" price: "€ 136.36" currency: EUR in_stock: true reviews_count: 13 url: https://www.desertcart.be/products/48639981-maxxisame-sam-e-powder-for-dogs-liver-and-cognitive-support store_origin: BE region: Belgium --- # Easy mix powder for all dog sizes Supports cognitive & dopamine health 150g pure SAM-e powder maxxiSAMe SAM-e Powder for Dogs - Liver & Cognitive Support 150g | Promotes hepatic function, mental sharpness, mood, energy and healthy ageing with artichoke, B vitamins and nutrients **Brand:** maxxipaws **Price:** € 136.36 **Availability:** ✅ In Stock ## Summary > 🐕‍🦺 Elevate your dog’s golden years with maxxiSAMe—because every moment counts! ## Quick Answers - **What is this?** maxxiSAMe SAM-e Powder for Dogs - Liver & Cognitive Support 150g | Promotes hepatic function, mental sharpness, mood, energy and healthy ageing with artichoke, B vitamins and nutrients by maxxipaws - **How much does it cost?** € 136.36 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.be](https://www.desertcart.be/products/48639981-maxxisame-sam-e-powder-for-dogs-liver-and-cognitive-support) ## Best For - maxxipaws enthusiasts ## Why This Product - Trusted maxxipaws brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Universal Fit:** Perfect for every breed and size, supporting joints, mood, and vitality. - • **Liver Powerhouse:** Boosts glutathione for natural liver regeneration and detox. - • **Effortless Dosing:** Powder form mixes seamlessly with food—no pills, no hassle. - • **All-in-One Wellness:** Includes artichoke, B vitamins, choline & inositol for holistic support. - • **Brain Boost Formula:** Enhances dopamine activity to keep your dog sharp and happy. ## Overview maxxiSAMe is a premium 150g SAM-e powder supplement designed to support liver health, cognitive function, and joint comfort in dogs of all breeds and sizes. Featuring a proprietary blend of SAM-e, artichoke leaf, B vitamins, choline, and inositol, this non-GMO, human-grade formula promotes natural liver regeneration, mental sharpness, and positive mood. Easy to administer by mixing into food, maxxiSAMe is crafted under GMP standards in the USA to ensure quality and effectiveness for your dog’s overall wellness. ## Features - LIVER SUPPORT FOR DOGS: maxxiSAMe is a SAM-e supplement for dogs made to support healthy liver (hepatic) function. SAM-e helps raise glutathione levels, which supports the liver's own cell regeneration and everyday work at any age. - COGNITIVE & BRAIN SUPPORT: As dogs age, maxxiSAMe supports cognitive function and mental sharpness. SAM-e helps support healthy dopamine activity in the brain, which may aid alertness and a positive mood in senior and older dogs. - ADDITIONAL NATURAL INGREDIENTS: More than just SAM-e. Artichoke leaf supports healthy bile production, B Vitamins support liver metabolism, and Choline plus Inositol support the liver's handling of fatty deposits. Non-GMO, human grade. - FOR ALL DOGS: Suitable for every breed and size, small, medium and large. maxxiSAMe supports joint comfort and a positive mood, and may help support alertness and mental sharpness in senior or older dogs. GMP made. - EASY POWDER, GIVEN WITH FOOD: Unlike hard to give tablets, maxxiSAMe is a natural flavor powder you simply mix into food for quick absorption. Add 1 scoop daily per 30 lb of body weight; the daily dose can be split for accurate dosing. ## Technical Specifications | Specification | Value | |---------------|-------| | Age Range Description | All Life Stages | | Allergen Information | Allergen-Free, Gluten Free, Seafood Free | | Animal Food Diet Type | Limited Ingredient | | Animal Food Ingredient Claim | Additive-Free | | Asin | B00ZD4IOV0 | | Benefits | Promotes liver health and brain function in aging animals | | Best Sellers Rank | 12,687 in Pet Supplies (See Top 100 in Pet Supplies) 159 in Hip & Joint Care for Dogs 286 in Supplements & Vitamins for Dogs | | Brand Name | maxxipaws | | Breed Recommendation | All Breed Sizes | | Container Type | Bag | | Country Of Origin | USA | | Customer Reviews | 4.2 4.2 out of 5 stars (902) 4.2 out of 5 stars | | Dog Breed Size | Medium | | Flavour | Natural | | Item Form | Powder | | Item Weight | 204 Grams | | Manufacturer | maxxipaws | | Manufacturer Part Number | MD-MS100 | | Model Number | MSA-2015 | | Number Of Items | 1 | | Occasion | Birthday | | Package Size Name | 150g | | Pet Type | Dog | | Recommended Uses For Product | Liver, cognitive and joint support | | Special Features | Cognitive Support (second use), Contains SAM-e, a compound not found in food, Powder form for easy administration, Additional supportive ingredients, Proprietary formula, High-quality manufacturing standards, No Artificial Additives, Non-GMO | | Special Ingredients | S-adenosylmethionine (SAM-e), artichoke leaf extract, choline, inositol, pantothenic acid, thiamine, riboflavin, vitamin B6, vitamin B12 | | Specific Uses For Product | Cognitive function, Joint support, Liver support | | Target Species | Dog | | Unit Count | 150.0 gram | ## Product Details - **Age range (description):** All Life Stages - **Brand:** maxxipaws - **Flavour:** Natural - **Item form:** Powder - **Specific uses for product:** Cognitive function, Joint support, Liver support ## Images ![maxxiSAMe SAM-e Powder for Dogs - Liver & Cognitive Support 150g | Promotes hepatic function, mental sharpness, mood, energy and healthy ageing with artichoke, B vitamins and nutrients - Image 1](https://m.media-amazon.com/images/I/71byHPWDznL.jpg) ## Available Options This product comes in different **Size Name** options. ## Questions & Answers **Q: Is this suitable for cats?** A: Thank you for your question and for your interest in our product. maxxiSAMe is suitable for both dogs and cats. We actually offer a smaller container specifically for cats. It is the same product (ingredients) but it comes in a smaller container (90 gr instead of 150 gr), making it more suitable size for single cat households. It also comes with a smaller scoop (1 g instead of 2.5 g), as cats servings as significantly smaller than most dogs. Still, many cat owners buy the dog version, especially those with many cats that needs maxxiSAMe for either liver or cognitive function. We hope this helps but if there is anything else that we may be able to assist you with, please be in touch and we will do everything we can to support you and your cat. In the meantime, we wish you and your cat all the best. Kind regards, Asa and Birgir Gislason Owners of maxxipaws **Q: Is this product vegetarian - our dog has allergies and can't have meat or fish derived things?** A: Thank you very much for your interest in maxxiSAMe which we really appreciate. maxxiSAMe is a fully natural supplement and does not contain any meat or fish, nor does it contain any artificial flavours, colours, preservatives or binders. The ingredients in the product are shown further down on the listing and also in photo 7 at the top of the listing. We hope this helps but if there is anything else we can assist you with, please don’t hesitate to contact us directly through your Amazon account. Kind regards, Alison Slater Customer Service Manager maxxipaws **Q: Is this ok to be given alongside salmon oil?** A: Thank you very much for your interest in maxxiSAMe which we really appreciate. maxxiSAMe is a fully natural supplement and as such can normally be given alongside other natural supplements. However, if a dog has a specific medical condition and / or is taking any medication or undergoing any kind of Veterinary treatment, we do recommend consulting your Vet before giving any new supplementation, just to be on the safe side. We hope this helps but if there is anything else we can assist you with, please don’t hesitate to contact us directly through your Amazon account. Kind regards, Alison Slater Customer Service Manager maxxipaws **Q: Should you give maxxisame powder to a healthy dog?** A: Thank you for your question and for your interest in our product. maxxiSAMe contains only natural ingredients. Most of our customers do use it for specific health conditions (to support liver, cognitive and joint health) but it is perfectly fine to give maxxiSAMe to healthy dogs as well. maxxiSAMe actually offers excellent health support for healthy senior dogs. We have 2 healthy senior dogs ourselves (9 and 11 years old) and we give them maxxiSAMe every other day as a general health support. We hope this helps but if there is anything else that we may be able to assist you with, please be in touch. Kind regards, Asa and Birgir Gislason Owners of maxxipaws ## Customer Reviews ### ⭐⭐⭐⭐⭐ MIRACLE PRODUCT *by on Reviewed in the United Kingdom 10 September 2024* MIRACLE PRODUCT!! This in my opinion is the two words that sum up this product; the results to me have been astounding, and I truly do believe this product has saved my dog (Shankly’s) life. I have attached photos from his blood tests prior to have his supplements and his blood test 7 weeks later, after having 7 weeks worth of supplements, just so you can see the difference!!This is going to be a very in-depth review, so please bear with me on this. So in a nutshell and a quick brief on my dogs background/medical history; he is on steroids for the rest of his life due to a medical condition known in short as MMM, basically this is where his immune system attacked his jaw and head muscles and caused severe and excruciating painful inflammation, in order for this condition to be kept at bay he requires steroids for the rest of his life. Obviously steroids are known to be very hard on the liver long term, we monitor his bloods regularly, and unfortunately his liver was showing signs of strain on his last blood test, so we were advised to put him on liver supplements. He did have bloods done a month and half prior to this and all was ok, but I felt something wasn’t quite right with him as he appeared tired all the time, to the point he looked shattered, and was showing less enthusiasm on his walks, so I went in with a full blood panel at the vets, and this is when we received news that his liver was showing signs of strain.The vet recommended Samylin, which we were willing to put him on, this would cost us £140 per month for him to be placed on these supplements. I wanted to source a more natural alternative if possible, and hopefully something what was more affordable. I come across this product on Amazon, read all the reviews and looked at the ingredients in MaxxiSAMe to see how they compared to Samylin.I gave MaxxiPaws a call, they were absolutely fantastic; I was obviously very upset when I called due to blood test results, the lady on the phone was able to calm me down, she listened to what I had to say without rushing me and explained about the MaxxiSAMe product, they also emailed me information about their product and FAQ’s, and hints and tips on how to administer the supplement powder. I obviously sent the information the MaxxiPaws team sent me, across to my vet, who confirmed it contained the same as the (expensive) Samylin, alongside extra added vitamins and said this would be ok to place Shankly on. The only difference the vet stated, is that silybin/silymarin component comes from the artichoke plant, as opposed to the milk thistle plant. But looking into this myself, and also in discussing this with the MaxxiPaws team, the artichoke is the better source for the silybin/silymarin to come from. The dosage for the main components that is used in the MaxxiSAMe, is the same as the Samylin therefore you are getting the exact same product as what the vet prescribed, but at a fraction of the cost, and you also get the added benefits of the extra vitamins, so you get a lot more bang for your buck.Within a couple of days of Shankly taking the supplement I noticed he appeared to be getting more energy, although it was very subtle at this stage, he seemed to be awake more and have more pep in his step, by day 3, his increase in energy levels were more noticeable, and more people were noticing this, not just myself. This made me super happy and was an absolute joy to see! I thought something must be moving in the right direction due to what I am seeing, his movements were a lot quicker, he was running up and down the stairs a lot quicker, jumping in the car a lot quicker, showing more enthusiasm when asking if he wanted to go on a walk, and also wasn’t laying down immediately after a walk. I would say after 3 weeks his energy levels were what they had been prior to his liver being under strain, at this point, me and my husband were feeling quietly confident that his next set of bloods would show improvement. The MaxxiPaws team were also optimistic to, as they said this is one of the first things a lot of owners noticed when they first gave their dog the supplement, the increase in energy levels.Shankly’s bilirubin levels, and bile acids were the main concern, as they were tittering on the edge of the ‘safe parameters’, although they were out of the normal range, his bilirubin was three times higher than what it should have been. He has been on this supplement for 6 and half weeks, to be precise, and on the recent blood test, his bilirubin was back in the normal parameters, as was his bile acids levels, and the rest of the liver enzymes! I was shocked, at how well his body has taken the supplement, I knew we would see a decrease in the enzyme levels, but not this much. It’s pretty amazing in such a short time frame his liver is operating healthily now and not showing signs of strain, I was absolutely over the moon with the results, and how much this has helped my boy. I cried with relief when we got those results in, and with tears of joy and happiness. This for me, is nothing short of a miracle,I honestly can’t thank the company MaxxiPaws enough for what their product has done for my dog, I truly believe they have saved his life. Not only that, but the support MaxxiPaws have provided me throughout these past 7 weeks has been phenomenal, I have been a nervous wreck due to worrying about my dog and his liver enzymes, the MaxxiPaws team have been there to support me every step of the way, allowing me to keep my anxiety under control and helping me to remain more optimistic. I have regularly kept in contact with them, to update them on Shanklys progress; they are always very happy to hear how well Shankly has been doing, and always get back to me. I wish more companies had the response to their customers that MaxxiPaws have; their customer service is impeccable, you really do feel, and know, that they are pet owners themselves and they take great pride and care in everything they do, they are such genuinely nice and caring people who’re keen to help your pet, and also to support you as an owner, through a tough time (as I found dealing with the liver enzyme issues of Shankly, very worrying and upsetting). It’s just so rare especially in the pet industry where you come across such an amazing company and a team of people (MaxxiPaws), who care as much as they do! For that I am truly, truly grateful, so much so that I feel words cannot express how grateful I am to them.Back on to the supplement, it is in powder form, which makes it fantastic to mix in with food. Shankly has his kibble soaked, and I add a quarter of a can of tuna in spring water and mix into a small portion of his kibble, to ensure he eats it all. He was a bit fussy at first, as dogs can be with new tasting things, but we got it down him, and this product works wonderfully, which is the main thing. Once he’s eaten this portion the rest of his meal is then placed down. The supplement comes with a scoop, allowing you to measure out the portion, and they recommend this is split between two meals, which we have been doing. His dose was double for the first few weeks, to help give his liver a good boost, and then the dose reduced a little bit more, and currently, 6 weeks in, he is on the maintenance dose. The MaxxiPaws team helped me with the support of what dose to place him on and then when to reduce it, as I just wanted to be sure that everything I was doing was correct and his liver was receiving the best support possible. Shankly weighs 27kg so using his maintenance dose of MaxxiSAMe, the tub lasts approximately a month.Shankly will remain on this supplement for the rest of his life, but I am perfectly fine with that, it’s all natural, which is fantastic for him and allows me to use the product with more confidence. I feel confident that all will be well now with Shankly and the continued use of supplements alongside his current medication which he has to have.I order mainly now, through their website, my first order was placed via Amazon as that’s where I initially saw the product, but, I have since joined the ‘MaxxiClub’ and receive a discount on any products I order through their website, you are also entered into a draw when you join the MaxxiClub, so you get a chance to win a free product in their draw, which is another perk. They donate to charities also, on a monthly basis, which is such a great thing for them to do as company, as I doubt many other companies have such kind gestures.Would I recommend this product to anybody whose dog has liver issues?! You bet I would. This product to my dog, has been a life saver, the results showing in his recent blood works are fantastic! I would without a shadow of a doubt recommend this product to any dog who needs it, I would also confidently use any of MaxxiPaws products on my dog if needs be, as I have that much confidence in their products and the company.April Update 2026 - My dogs blood tests come back as very good again, so happy that the product is continuing to do the good work. ### ⭐⭐⭐⭐⭐ Liver cancer *by on Reviewed in the United Kingdom 3 May 2026* Just about to order my 3rd tub. My border collie was diagnosed last year with liver cancer, which was causing her pancreas and kidney levels to become very elevated. She had very sloppy stools and was going 4 times a day. Within a couple of days of giving her this supplement I noticed a big improvement in the quality of what was coming out of her rear end; also the number and size of stools reduced. Additionally, she had been looking very dozy and is much more her lively self now. I cannot comment on whether or not it has reduced her liver count as this is no longer being tested. You may find that, to get results, you do not need as much as it says on the container. I give her one scoop a day, which is less than what is suggested, and the tub lasts 3 months. To reply to some comments in other reviews. The powder is a bit bitter (I tried it myself) but my dog happily eats it in her food spread over 4 meals a day. I do mix it in well. I don't find it goes lumpy, but I do leave the silica packet in the tub and give the MaxiSame powder a good stir around every so often. For those people saying there isn't much powder in the container, it is sold by weight not volume. It's not a miracle cure but I do think that it is giving me a bit more time with my dog as I originally didn't think she'd get past Christmas. The only negative is that it is a shame the company doesn't offer a trial size for people to try it out as it is an expensive purchase. ### ⭐⭐⭐⭐ Liver supplement for dog *by on Reviewed in the United Kingdom 24 May 2026* Replaced instead of a tablet version and so far no issues. ## Frequently Bought Together - maxxipaws maxxiSAMe Advanced SAM-e Powder Supplement - Liver, Cognitive & Joint Support for Dogs, 5.3oz - maxxipaws maxxidigest+ Prebiotic & Probiotic for Dogs 13.2oz | Dog Probiotic Powder with Advanced Digestive Enzymes for Gut Health & Immunity | Supports Digestion, Food Sensitivities & Itchy Skin - maxxipaws maxxiomega Omega 3, 6 & 9 Oil Supplement - Skin & Coat Support for Dogs, 10oz --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.be/products/48639981-maxxisame-sam-e-powder-for-dogs-liver-and-cognitive-support](https://www.desertcart.be/products/48639981-maxxisame-sam-e-powder-for-dogs-liver-and-cognitive-support) --- *Product available on Desertcart Belgium* *Store origin: BE* *Last updated: 2026-09-04*