---
product_id: 253690400
title: "THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings"
brand: "thorne"
price: "€ 131.45"
currency: EUR
in_stock: true
reviews_count: 5
category: "Thorne"
url: https://www.desertcart.be/products/253690400-thorne-methyl-guard-plus-active-folate-5-mthf-with-vitamins
store_origin: BE
region: Belgium
---

# 90 capsules, 30 servings for monthly supply 5-MTHF active folate for optimal methylation Supports heart & brain health with B vitamins THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings

**Brand:** thorne
**Price:** € 131.45
**Availability:** ✅ In Stock

## Summary

> 🧠 Elevate your wellness game with the methylation masterclass!

## Quick Answers

- **What is this?** THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings by thorne
- **How much does it cost?** € 131.45 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.be](https://www.desertcart.be/products/253690400-thorne-methyl-guard-plus-active-folate-5-mthf-with-vitamins)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clinically Trusted Quality:** Backed by 4 rigorous testing rounds and trusted by 100+ pro sports teams and healthcare practitioners worldwide.
- • **Optimized for Adult Wellness:** 90 capsules provide a convenient 30-day regimen designed for busy professionals prioritizing long-term vitality.
- • **Clean & Allergen-Free Formula:** Gluten, dairy, and soy-free to fit seamlessly into your clean-living, health-conscious lifestyle.
- • **Precision Methylation Support:** Harness the power of active folate (5-MTHF) and methylcobalamin B12 for superior nutrient absorption and balanced homocysteine levels.
- • **Cognitive & Cardiovascular Boost:** Promotes neurotransmitter production and cellular energy to keep your brain sharp and heart strong.

## Overview

THORNE Methyl-Guard Plus delivers a potent blend of active folate (5-MTHF) and B vitamins B2, B6, and B12 to support healthy methylation and maintain optimal homocysteine levels. This gluten, dairy, and soy-free formula is rigorously tested for purity and efficacy, trusted by elite athletes and healthcare professionals alike. Designed for adults seeking enhanced cardiovascular and cognitive health, it offers a clean, convenient 30-serving supply to fuel your daily wellness journey.

## Description

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Review: MTHFR - High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.
Review: Just what the doctor ordered! - Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Brand | THORNE |
| Flavour | Unflavored |
| Item form | Capsule |
| Item weight | 109 g |
| Primary supplement type | Riboflavin |
| Unit count | 90.0 Count |

## Product Details

- **Age range (description):** Adult
- **Brand:** THORNE
- **Diet type:** Gluten Free
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 6 x 6 x 10.7 centimeters
- **Item form:** Capsule
- **Item weight:** 0.24 Pounds
- **Primary supplement type:** Riboflavin
- **Product benefits:** Eye Health
- **Unit count:** 90.0 Count

## Images

![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 1](https://m.media-amazon.com/images/I/611fI5u7HYL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 2](https://m.media-amazon.com/images/I/71+ttyxERbL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 3](https://m.media-amazon.com/images/I/71+mLMs9inL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 4](https://m.media-amazon.com/images/I/81kXNNJzXaL.jpg)
![THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine - Gluten, Dairy & Soy-Free - 90 Capsules - 30 Servings - Image 5](https://m.media-amazon.com/images/I/61kxlFQHo2L.jpg)

## Available Options

This product comes in different **Set** options.

## Questions & Answers

**Q: What makes Thorne supplements high quality?**
A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption.

**Q: How does Thorne test its supplements for quality?**
A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we produce. 100+ Thorne employees are dedicated to ensuring quality.

**Q: Are Thorne supplements clinically Reviewed and safe?**
A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature.

**Q: Why are Thorne products more expensive than other supplements?**
A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard.

**Q: Where are Thorne supplements made and where are the ingredients sourced from?**
A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

## Customer Reviews

### ⭐⭐⭐⭐⭐ MTHFR
*by J***N on 12 October 2025*

High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.

### ⭐⭐⭐⭐⭐ Just what the doctor ordered!
*by L***. on 25 February 2025*

Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need.

### ⭐⭐⭐⭐⭐ Vitamins
*by S***E on 16 March 2026*

Great vitamins that give good energy

## Frequently Bought Together

- THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
- THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules
- THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules

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---

*Product available on Desertcart Belgium*
*Store origin: BE*
*Last updated: 2026-06-14*