---
product_id: 253690400
title: "Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings"
brand: "thorne"
price: "€ 129.86"
currency: EUR
in_stock: true
reviews_count: 5
category: "Thorne"
url: https://www.desertcart.be/products/253690400-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2
store_origin: BE
region: Belgium
---

# Methylcobalamin B12 for superior absorption 4 rounds of rigorous purity & potency testing 5-MTHF active folate for optimal methylation Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings

**Brand:** thorne
**Price:** € 129.86
**Availability:** ✅ In Stock

## Summary

> 🧬 Elevate your wellness game with the methylation masterclass!

## Quick Answers

- **What is this?** Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings by thorne
- **How much does it cost?** € 129.86 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.be](https://www.desertcart.be/products/253690400-methyl-guard-plus-active-folate-5-mthf-with-vitamins-b2)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Neuro & Heart Synergy:** Supports cardiovascular health and brain function by enhancing neurotransmitter production and cellular energy.
- • **Clean & Pure Assurance:** Gluten, dairy, and soy-free with 4 rounds of lab testing guaranteeing purity and potency in every capsule.
- • **Millennial-Ready Wellness:** Unflavored, easy-to-take capsules designed for busy professionals prioritizing peak health and longevity.
- • **Clinically Trusted Formula:** Chosen by 100+ pro sports teams and top healthcare practitioners, ensuring elite-grade quality and efficacy.
- • **Precision Methylation Support:** Harness the power of active folate (5-MTHF) and methyl donors to optimize your body's methylation process and maintain healthy homocysteine levels.

## Overview

THORNE Methyl-Guard Plus delivers active folate (5-MTHF) alongside vitamins B2, B6, and methylcobalamin B12 to support healthy methylation and maintain optimal homocysteine levels. Backed by rigorous 4-stage testing and trusted by elite athletes and healthcare pros, this gluten, dairy, and soy-free formula promotes cardiovascular and brain health, making it a top-tier choice for adults seeking advanced nutritional support.

## Description

THORNE Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings : desertcart.ae: Automotive

Review: MTHFR - High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.
Review: Just what the doctor ordered! - Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need.

## Features

- Healthy Methylation: Provides B vitamins and other nutrients that optimize methylation and promote a healthy level of homocysteine in the bloodsteam*
- Active Forms: Formulated with superior methyl donors, including betaine and active folate (5-MTHF) and B12 (as methylcobalamin), to optimize utilization in the body
- Heart and Brain Benefits: Sustains cardiovascular health and promotes healthy brain function by supporting neurotransmitter production and enhancing cellular energy levels*
- 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00O5AHC4S |
| Age Range Description | Adult |
| Best Sellers Rank | #5,268 in Health ( See Top 100 in Health ) #245 in Multivitamins Nutritional Supplements |
| Brand | THORNE |
| Brand Name | THORNE |
| Color | red |
| Country of Publication | USA |
| Customer Reviews | 4.7 out of 5 stars 1,645 Reviews |
| Diet Type | Gluten Free |
| Dosage Form | Capsules |
| Flavor | Unflavored |
| Flavour | Unflavored |
| Global Trade Identification Number | 00693749789017 |
| Item Dimensions | 6 x 6 x 10.7 centimeters |
| Item Form | Capsule |
| Item Weight | 0.24 Pounds |
| Item form | Capsule |
| Item weight | 0.24 Pounds |
| Manufacturer | Thorne Research |
| Manufacturer Part Number | SF789 |
| Material Features | Dairy Free, Gluten Free |
| Material Type Free | en_AE |
| Model Name | Methyl-Guard Plus |
| Model Number | No Model |
| Number of Items | 1 |
| Primary Supplement Type | Riboflavin |
| Primary supplement type | Riboflavin |
| Product Benefits | Eye Health |
| Specific Uses For Product | Heart |
| UPC | 693749789017 701627510421 884967152206 882855267766 885786045052 |
| Unit Count | 90.0 Count |
| Unit count | 90.0 Count |

## Product Details

- **Age range (description):** Adult
- **Brand:** THORNE
- **Diet type:** Gluten Free
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 6 x 6 x 10.7 centimeters
- **Item form:** Capsule
- **Item weight:** 0.24 Pounds
- **Primary supplement type:** Riboflavin
- **Product benefits:** Eye Health
- **Unit count:** 90.0 Count

## Images

![Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten, Dairy & Soy-Free - 30 Servings - Image 1](https://m.media-amazon.com/images/I/611fI5u7HYL.jpg)

## Available Options

This product comes in different **Style** options.

## Questions & Answers

**Q: What makes Thorne supplements high quality?**
A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption.

**Q: How does Thorne test its supplements for quality?**
A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we manufacture. 100+ Thorne employees are dedicated to ensuring quality.

**Q: Are Thorne supplements clinically tested and safe?**
A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature.

**Q: Why are Thorne products more expensive than other supplements?**
A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard.

**Q: Where are Thorne supplements made and where are the ingredients sourced from?**
A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

## Customer Reviews

### ⭐⭐⭐⭐⭐ MTHFR
*by J***N on 12 October 2025*

High quality B complex! Helpful for MTHFR gene mutation. I have been using them for about six months now and notice a huge difference in my cycle regularity, as it has very high amounts of B6 and a methylated form, I’m convinced is due to this product. My menstrual cramps have all but almost completely disappeared, which is absolutely amazing considering I have struggled with that since my teens could not recommend this more, especially for women struggling with similar issues.

### ⭐⭐⭐⭐⭐ Just what the doctor ordered!
*by L***. on 25 February 2025*

Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need.

### ⭐⭐⭐⭐⭐ Vitamins
*by S***E on 16 March 2026*

Great vitamins that give good energy

## Frequently Bought Together

- THORNE Methyl-Guard Plus - Active folate (5-MTHF) with Vitamins B2, B6 & B12 - Supports methylation & Healthy Level of homocysteine* - Gluten, Dairy & Soy-Free - 90 Capsules
- THORNE Magnesium CitraMate - Magnesium Supplement with Citrate-Malate - Support Heart, Skeletal Muscles, Cardiac, Lung Function, and Bone Density* - Gluten-Free, Dairy-Free, Soy-Free - 90 Capsules
- THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules

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---

*Product available on Desertcart Belgium*
*Store origin: BE*
*Last updated: 2026-05-25*