While common moisturizers dissipate quickly, advancedThePure Guild Moisturizing Treatment strengthens and rebuilds the barrier function of the stratum corneum to retain innate moisture and resist environmental assault. Pure Guild achieves such intense moisturization because its active ingredient, Pichia anomala extract, stimulates lamellar-lipid transport, synthesis, and maturation within the epidermis. Pichia anomala recruits exogenous lipids into the keratinocytes, as demonstrated by a 33 percent increase in fatty-acid transport proteins. Inside skin cells, the extract stimulates lipid synthesis, measured as a 25 percent increase in the expression of lamellar-body proteins. For optimum integrity, the extract stimulates formation of lipid lamellae to seal intercellular spaces, as indicated by a 38 percent boost in key enzyme activity. Reinforcing the barrier function at the cellular level means Pure Guild Moisturizing Treatment truly controls transepidermal water loss to retain natural moisture, so skin looks and feels young and healthy.
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