These plates are coated with AVICEL microcrystalline cellulose manufactured by the American Viscose division of FMC Corp. The adsorbent consists of regenerated alpha cellulose particles of nearly spherical shape and 50 micron mean diameter. Compounds separated on this cellulose tend to form more compact spots than on fibrous cellulose layers. Preparative TLC plates have adsorbent layers thicker than the 250 micron layers normally used for analytical separations. Thus, preparative plates can be used for separation of larger quantities of materials.The loading capacity for a given degree of sample component resolution increases roughly as the square root of the increased adsorbent layer thickness. In preparative TLC, materials to be separated are often applied as long streaks rather than spots. After development, specific compounds may be recovered by scraping the adsorbent layers from the plate in the region of interest and eluting the separated material from the adsorbent using a strong solvent. Thicker layers for higher capacity Full range of plate sizes Prep-scored option for convenient zone location Available with preadsorbent sample loading zone Calcium sulfate binder-soft later for easy scraping
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