Mushroom Science Coriolus PSP (Turkey Tail)Also known as the turkey tail mushroom or Trametes versicolor, Coriolus versicolor enjoys a long history of use and recognition in Traditional Chinese Medicine with appearances in traditional herbal texts dating as far back as the early 15th century. Coriolus PSP was developed by Dr. Yang of the Shanghai Teachers College in the 1980's. Contrary to some claims, PSP and PSK can be produced from any strain of Coriolus versicolor and can be extracted from the mushroom fruit bodies or the mycelium, as long as the mycelium is grown through submerged culture in a liquid medium.Coriolus versicolor in HistoryDecoctions of Coriolus versicolor have been used for centuries in Traditional Chinese Medicine (TCM), with references in the Chinese Compendium of Materia Medica dating as far back as the 15th century.Coriolus PSP vs. PSKThe Coriolus extract called PSP (Polysaccharide-Peptide) was first developed in China during the late 1980s, about 15 years after the first studies on the Japanese extract PSK (a.k.a. Krestin or Coriolus Super Strength) were published.The main difference between the two extracts is that PSP contains both peptides and proteins in the non-glucan portion of the molecule, but contains more peptides than proteins. PSK also contains both peptides and proteins in the non-glucan portion of the molecule, but contains more proteins than peptides. PSP therefore is classified as a polysaccharide-peptide, PSK is classified as a protein-bound polysaccharide.There are also minor differences in the non-active single sugars, however, in the glucan portion of both PSP and PSK, the part considered to be biologically active for immune support purposes, is identical under NMR analysis (Nuclear Magnetic Resonance Imaging).This difference in the peptide-protein ratio between PSP and PSK is due to the fact
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